Shake Test

The shake test is a simple, rapid method used to check whether certain vaccines, particularly those containing aluminum adjuvants (like Penta, TT, and Hepatitis B), have been damaged by freezing. Freezing can cause these vaccines to lose their effectiveness, making the shake test an important quality control measure.

How to Perform the Shake Test

  1. Preparation:

    • Obtain a suspect vaccine,

    • Then take the normal one and prepare to be frozen by yourself.

      3. Labeling:

  • Label the suspect vaccine as “suspect.”

  • Label the normal vaccine as “control.”

  1. Shaking:

    • Shake both vaccines vigorously for 10–15 seconds.

  1. Observation:

    • Place the vials upside down.

    • Observe sedimentation (settling) within the vials.

  1. Interpretation:

    • If the suspect vaccine and the normal vaccine sediment together, the suspect vaccine may be frozen.

    • If the normal vaccine shows faster sedimentation than the suspect vaccine, the suspect vaccine is likely normal.

This method seems like a practical way to assess vaccine integrity. However, it’s essential to consult official guidelines and protocols for vaccine testing and quality control. Always rely on established scientific procedures when evaluating vaccines. 🌟

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